Science  •  Innovation  •  Sustainability  •  Excellence
Custom Synthesis
Molecules made to your specification

Custom Synthesis

Custom synthesis at Vean’s starts with the constraint that matters most to you — cost, purity, timeline or freedom to operate — and works backwards to the route. We evaluate the literature, design and screen alternatives, and hand back a process that is reproducible at the scale you actually need.

  • Literature route evaluation & benchmarking
  • Novel and non-infringing route design
  • Process optimisation for yield, cost and purity
  • Analytical method development & validation
  • Milligram to multi-kilogram delivery
  • Complete technical package & tech transfer
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Area Expertise
Therapeutic and industrial domains we know well

Area Expertise

Depth matters more than breadth in process chemistry. Our team has repeatedly delivered in the areas below, which means fewer surprises on impurity profiles, work-up behaviour and scale-up risk.

  • Oncology & targeted therapies
  • Cardiovascular
  • Central nervous system (CNS)
  • Anti-diabetic & metabolic
  • Anti-viral & anti-infective
  • Agrochemical and specialty segments
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Reaction Expertise
Reactions we run with confidence

Reaction Expertise

Difficult chemistry is where a partner earns their place. We maintain hands-on capability in reaction classes that many suppliers avoid — and the engineering discipline to run them safely at scale.

  • Cryogenic reactions (to −78 °C)
  • Catalytic hydrogenation & high-pressure chemistry
  • Chiral chemistry & asymmetric synthesis
  • Organometallics — Grignard, organolithium
  • Coupling reactions — Suzuki, Heck, Buchwald
  • Oxidations, reductions, halogenations & nitrations
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Working With Our R&D

Your chemistry stays yours

Every custom synthesis and CRAMS engagement is governed by confidentiality and clear IP ownership before any work begins.

Confidentiality First

Mutual NDA before technical discussion. Structures, routes and data are shared only with the assigned project team.

Complete Technical Package

Process description, analytical methods, spectral data and batch records handed over on completion.

Scalable by Design

Routes are assessed for safety, cost and scalability from the first experiment — not retro-fitted later.

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Have a difficult molecule?

Send us the structure or the CAS number under NDA — our research team will come back with a route assessment and an honest view on feasibility.